Best Cassiopeia Build on Mid for patch 15.10. Find the Cassiopeia Runes you are looking for!
1.7%
Pick Rate
49.5%
Win Rate
1.5%
Ban Rate
43,800
Matches
Summoner Spells


49.5%
34,742 Matches
Starter Items

2

49.8%
30,396 Matches
Core Items



54.1%
11,991 Matches
Late Game Items



53.2%59.5%55.2%
Spell Skill Priority

E

Q

W
55%
6,473 Matches

Q
2
8
10
12
13

W
4
14
15

E
1
3
5
7
9

R
6
11
Cassiopeia Runes

































lolvvv Cassiopeia Runes
Cassiopeia Runes

0%

0%

0%

100%

0%

1%

99%

0%

100%

0%

0%

39%

61%


0%

100%

0%

88%

0%

0%

12%

0%

0%

75%

2%

23%

85%

1%

0%

46%

0%

40%
Lore
Ally Tips
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Enemy Tips
Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.
Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.
Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.