Twitch Build / Runes
Late Game Items
Spell Skill Priority
lolvvv Twitch RunesTwitch Runes
Press the Attack
Presence of Mind
Coup de Grace
Taste of Blood
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Highest Pick Rate22.6%
Highest Win Rate53.7%
Twitch Runes's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch Runes is fragile. Work with teammates to focus on him when you're able to catch him out of Camouflage.
Spell Shields won't block the damage from Deadly Venom, but they will block the effects Twitch Runes can trigger with it.
If you suspect Twitch Runes has left the lane, let your teammates know that Twitch Runes is ''MIA.''