Cassiopeia Build / Runes
4

Cassiopeia Build / Runes

the Serpent's Embrace • Platinum+
Best Cassiopeia Build on Adc for patch 12.1. Find the Cassiopeia Runes you are looking for!
0.3%
Pick Rate
54.4%
Win Rate
1.6%
Ban Rate
4.8K
Matches

Strong against

Weak against

Summoner Spells

Exhaust
Flash
55.5%
2,079 Matches

Starter Items

Health Potion
2
Tear of the Goddess
55.3%
4,126 Matches

Core Items

Everfrost
Cosmic Drive
Archangel's Staff
74.7%
166 Matches

Late Game Items

Zhonya's Hourglass
Rylai's Crystal Scepter
Rabadon's Deathcap
55.8%
58.8%
61.6%

Spell Skill Priority

Twin Fang
E
Noxious Blast
Q
Miasma
W
59.9%
1,096 Matches
Noxious Blast
2
8
10
12
13
 
Miasma
4
14
15
 
Twin Fang
1
3
5
7
9
 
Petrifying Gaze
6
11
 

Mobalytics Cassiopeia Runes

More Cassiopeia Builds
Precision

Precision

Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Domination

Domination

Cheap Shot
Taste of Blood
Sudden Impact
Zombie Ward
Ghost Poro
Eyeball Collection
Ravenous Hunter
Ingenious Hunter
Relentless Hunter
Ultimate Hunter
Offense
Offense
Defense
Offense
Flex
Flex
Offense
Flex
Flex

lolvvv Cassiopeia Runes

Cassiopeia Runes
Precision

Precision

Press the Attack
0%
Lethal Tempo
0%
Fleet Footwork
0%
Conqueror
100%
Overheal
0%
Triumph
0%
Presence of Mind
100%
Legend: Alacrity
0%
Legend: Tenacity
100%
Legend: Bloodline
0%
Coup de Grace
100%
Cut Down
0%
Last Stand
0%
Domination

Domination

Cheap Shot
0%
Taste of Blood
83%
Sudden Impact
0%
Zombie Ward
0%
Ghost Poro
0%
Eyeball Collection
17%
Ravenous Hunter
100%
Ingenious Hunter
0%
Relentless Hunter
0%
Ultimate Hunter
0%
Offense
100%
Offense
100%
Defense
0%
Offense
0%
Flex
0%
Flex
17%
Offense
0%
Flex
0%
Flex
83%

opgg Cassiopeia Runes

Highest Pick Rate

33.6%
Precision

Precision

Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Domination

Domination

Cheap Shot
Taste of Blood
Sudden Impact
Zombie Ward
Ghost Poro
Eyeball Collection
Ravenous Hunter
Ingenious Hunter
Relentless Hunter
Ultimate Hunter
Offense
Offense
Defense
Offense
Flex
Flex
Offense
Flex
Flex

Highest Win Rate

57.0%
Precision

Precision

Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Domination

Domination

Cheap Shot
Taste of Blood
Sudden Impact
Zombie Ward
Ghost Poro
Eyeball Collection
Ravenous Hunter
Ingenious Hunter
Relentless Hunter
Ultimate Hunter
Offense
Offense
Defense
Offense
Flex
Flex
Offense
Flex
Flex

Lore

Ally Tips

Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.

Lead your enemy when targeting with Noxious Blast to ensure the hit.

Enemy Tips

Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.

Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.

Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.