Cassiopeia
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Cassiopeia Build / Runes

the Serpent's Embrace • Platinum+
TOPJUNGLEMIDDLEADCARRYSUPPORT
Best Cassiopeia Build on Mid for patch 13.19. Find the Cassiopeia Runes you are looking for!
2%
Pick Rate
50.9%
Win Rate
2%
Ban Rate
91,464
Matches

Strong against

LeBlanc
42.1%
1,488
Azir
44.3%
1,230
Irelia
46%
1,907
Akshan
46.6%
1,322
Tristana
46.7%
1,584

Weak against

Anivia
53.2%
924
Syndra
52.9%
3,274
Xerath
52.9%
1,982
Talon
52.4%
1,648
Malzahar
52.2%
2,224

Summoner Spells

FlashTeleport
50.9%
65,784 Matches

Starter Items

Health Potion
2
Tear of the Goddess
51.5%
76,368 Matches

Core Items

Rod of Ages
Archangel's StaffRylai's Crystal Scepter
57.7%
20,295 Matches

Late Game Items

Zhonya's Hourglass
Rabadon's Deathcap
Void Staff
54.6%62.5%58.7%

Spell Skill Priority

Twin Fang
E
Noxious Blast
Q
Miasma
W
52%
52,118 Matches
Noxious Blast
Q
2
8
10
12
13
Miasma
W
3
14
15
Twin Fang
E
1
4
5
7
9
Petrifying Gaze
R
6
11

Cassiopeia Runes

PrecisionPrecision
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SorcerySorcery
Nullifying Orb
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
Offense
Offense
Offense
Offense
Flex
Flex
Defense
Flex
Flex

lolvvv Cassiopeia Runes

Cassiopeia Runes
PrecisionPrecision
Press the Attack
0%
Lethal Tempo
0%
Fleet Footwork
0%
Conqueror
100%
Overheal
0%
Triumph
0%
Presence of Mind
100%
Legend: Alacrity
3%
Legend: Tenacity
96%
Legend: Bloodline
1%
Coup de Grace
20%
Cut Down
0%
Last Stand
80%
SorcerySorcery
Nullifying Orb
0%
Manaflow Band
97%
Nimbus Cloak
1%
Transcendence
73%
Celerity
0%
Absolute Focus
1%
Scorch
28%
Waterwalking
0%
Gathering Storm
0%
Offense
43%
Offense
7%
Offense
51%
Offense
>99%
Flex
0%
Flex
0%
Defense
4%
Flex
30%
Flex
65%

Lore

Ally Tips

Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.

Lead your enemy when targeting with Noxious Blast to ensure the hit.

Enemy Tips

Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.

Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.

Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.