Cassiopeia Build / Runes
3

Cassiopeia Build / Runes

the Serpent's Embrace • Platinum+
Best Cassiopeia Build on Mid for patch 12.12. Find the Cassiopeia Runes you are looking for!
2.6%
Pick Rate
51.9%
Win Rate
2%
Ban Rate
37.8K
Matches

Strong against

Weak against

Summoner Spells

Exhaust
Flash
52.5%
9,191 Matches

Starter Items

Health Potion
2
Tear of the Goddess
52.0%
30,831 Matches

Core Items

Liandry's Anguish
Archangel's Staff
Rylai's Crystal Scepter
57.4%
6,970 Matches

Late Game Items

Zhonya's Hourglass
Rabadon's Deathcap
Demonic Embrace
55.1%
63.7%
60.4%

Spell Skill Priority

Twin Fang
E
Noxious Blast
Q
Miasma
W
52.9%
19,708 Matches
Noxious Blast
2
8
10
12
13
 
Miasma
3
14
15
 
Twin Fang
1
4
5
7
9
 
Petrifying Gaze
6
11
 

Mobalytics Cassiopeia Runes

More Cassiopeia Builds
Precision

Precision

Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Resolve

Resolve

Demolish
Font of Life
Shield Bash
Conditioning
Second Wind
Bone Plating
Overgrowth
Revitalize
Unflinching
Offense
Offense
Defense
Offense
Flex
Flex
Offense
Flex
Flex

lolvvv Cassiopeia Runes

Cassiopeia Runes
Precision

Precision

Press the Attack
0%
Lethal Tempo
0%
Fleet Footwork
0%
Conqueror
100%
Overheal
0%
Triumph
0%
Presence of Mind
100%
Legend: Alacrity
0%
Legend: Tenacity
100%
Legend: Bloodline
0%
Coup de Grace
50%
Cut Down
0%
Last Stand
50%
Resolve

Resolve

Demolish
0%
Font of Life
0%
Shield Bash
0%
Conditioning
21%
Second Wind
0%
Bone Plating
79%
Overgrowth
57%
Revitalize
0%
Unflinching
43%
Offense
52%
Offense
100%
Defense
5%
Offense
0%
Flex
0%
Flex
24%
Offense
48%
Flex
0%
Flex
71%

Lore

Ally Tips

Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.

Lead your enemy when targeting with Noxious Blast to ensure the hit.

Enemy Tips

Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.

Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.

Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.