3
Cassiopeia Build / Runes
the Serpent's Embrace • Platinum+
Best Cassiopeia Build on Mid for patch 12.22. Find the Cassiopeia Runes you are looking for!
2.6%
Pick Rate
50.9%
Win Rate
1.9%
Ban Rate
2.4K
Matches
Strong against
60.5%
38
60.5%
129
60.0%
30
57.4%
122
56.7%
30
Weak against
40.0%
35
40.7%
27
41.9%
43
42.9%
28
42.9%
42
Summoner Spells
51.8%
884 Matches
Starter Items
2
51.0%
1,894 Matches
Core Items
59.1%
330 Matches
Late Game Items
72.7%
58.8%
58.0%
Spell Skill Priority
E
Q
W
56.1%
576 Matches
| 2 Q | 8 Q | 10 Q | 12 Q | 13 Q | |||||||||||
| 4 W | 14 W | 15 W | |||||||||||||
| 1 E | 3 E | 5 E | 7 E | 9 E | |||||||||||
 | 6 R | 11 R |
Mobalytics Cassiopeia Runes
More Cassiopeia Builds
Precision
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Resolve
Demolish
Font of Life
Shield Bash
Conditioning
Second Wind
Bone Plating
Overgrowth
Revitalize
Unflinching
lolvvv Cassiopeia Runes
Cassiopeia RunesPrecision
0%
Press the Attack
0%
Lethal Tempo
0%
Fleet Footwork
100%
Conqueror
0%
Overheal
0%
Triumph
100%
Presence of Mind
0%
Legend: Alacrity
100%
Legend: Tenacity
0%
Legend: Bloodline
0%
Coup de Grace
0%
Cut Down
100%
Last Stand
Sorcery
0%
Nullifying Orb
100%
Manaflow Band
0%
Nimbus Cloak
100%
Transcendence
0%
Celerity
0%
Absolute Focus
0%
Scorch
0%
Waterwalking
0%
Gathering Storm
33%
100%
0%
0%
0%
0%
67%
0%
100%
Lore
Ally Tips
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Enemy Tips
Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.
Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.
Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.