4
Cassiopeia Build / Runes
the Serpent's Embrace • Platinum+
Best Cassiopeia Build on Adc for patch 12.1. Find the Cassiopeia Runes you are looking for!
0.3%
Pick Rate
54.4%
Win Rate
1.6%
Ban Rate
4.8K
Matches
Strong against
65.9%
123
61.1%
185
60.8%
74
59.3%
641
59.3%
162
Weak against
47.5%
122
47.6%
82
50.1%
599
51.9%
566
52.6%
190
Summoner Spells
55.5%
2,079 Matches
Starter Items
2
55.3%
4,126 Matches
Core Items
74.7%
166 Matches
Late Game Items
55.8%
58.8%
61.6%
Spell Skill Priority
E
Q
W
59.9%
1,096 Matches
| 2 Q | 8 Q | 10 Q | 12 Q | 13 Q | |||||||||||
| 4 W | 14 W | 15 W | |||||||||||||
| 1 E | 3 E | 5 E | 7 E | 9 E | |||||||||||
 | 6 R | 11 R |
Mobalytics Cassiopeia Runes
More Cassiopeia Builds
Precision
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Domination
Cheap Shot
Taste of Blood
Sudden Impact
Zombie Ward
Ghost Poro
Eyeball Collection
Ravenous Hunter
Ingenious Hunter
Relentless Hunter
Ultimate Hunter
lolvvv Cassiopeia Runes
Cassiopeia RunesPrecision
0%
Press the Attack
0%
Lethal Tempo
0%
Fleet Footwork
100%
Conqueror
0%
Overheal
0%
Triumph
100%
Presence of Mind
0%
Legend: Alacrity
100%
Legend: Tenacity
0%
Legend: Bloodline
100%
Coup de Grace
0%
Cut Down
0%
Last Stand
Domination
0%
Cheap Shot
83%
Taste of Blood
0%
Sudden Impact
0%
Zombie Ward
0%
Ghost Poro
17%
Eyeball Collection
100%
Ravenous Hunter
0%
Ingenious Hunter
0%
Relentless Hunter
0%
Ultimate Hunter
100%
100%
0%
0%
0%
17%
0%
0%
83%
opgg Cassiopeia Runes
Highest Pick Rate
33.6%Precision
Domination
Highest Win Rate
57.0%Precision
Domination
Lore
Ally Tips
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Enemy Tips
Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.
Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.
Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.