Cassiopeia
D

Cassiopeia Build / Runes

the Serpent's Embrace • Platinum+
TOPJUNGLEMIDDLEADCARRYSUPPORT
Best Cassiopeia Build on Mid for patch 14.4. Find the Cassiopeia Runes you are looking for!
1.9%
Pick Rate
51.7%
Win Rate
1.5%
Ban Rate
99,486
Matches

Strong against

Smolder
44.6%
1,669
LeBlanc
45.2%
1,651
Azir
45.5%
2,046
Sylas
45.9%
3,974
Orianna
46.6%
1,912

Weak against

Anivia
51.7%
1,010
Aurelion Sol
51.6%
3,005
Xerath
51.5%
1,464
Ekko
51.5%
1,669
Viktor
50.8%
1,504

Summoner Spells

FlashTeleport
51.5%
75,567 Matches

Starter Items

Health Potion
2
Tear of the Goddess
51.8%
74,121 Matches

Core Items

Rod of AgesArchangel's StaffRylai's Crystal Scepter
55.9%
25,782 Matches

Late Game Items

Liandry's Torment
Zhonya's Hourglass
Cosmic Drive
57.2%58.7%59.4%

Spell Skill Priority

Twin Fang
E
Noxious Blast
Q
Miasma
W
53%
54,532 Matches
Noxious Blast
Q
2
8
10
12
13
Miasma
W
3
14
15
Twin Fang
E
1
4
5
7
9
Petrifying Gaze
R
6
11

Cassiopeia Runes

PrecisionPrecision
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SorcerySorcery
Nullifying Orb
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
Offense
Offense
Offense
Offense
Flex
Flex
Defense
Flex
Flex

lolvvv Cassiopeia Runes

Cassiopeia Runes
PrecisionPrecision
Press the Attack
0%
Lethal Tempo
0%
Fleet Footwork
0%
Conqueror
100%
Overheal
0%
Triumph
0%
Presence of Mind
100%
Legend: Alacrity
0%
Legend: Tenacity
100%
Legend: Bloodline
0%
Coup de Grace
15%
Cut Down
0%
Last Stand
85%
SorcerySorcery
Nullifying Orb
0%
Manaflow Band
96%
Nimbus Cloak
1%
Transcendence
88%
Celerity
1%
Absolute Focus
0%
Scorch
12%
Waterwalking
0%
Gathering Storm
2%
Offense
47%
Offense
0%
Offense
53%
Offense
95%
Flex
1%
Flex
0%
Defense
54%
Flex
11%
Flex
15%

Lore

Ally Tips

Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.

Lead your enemy when targeting with Noxious Blast to ensure the hit.

Enemy Tips

Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.

Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.

Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.