Cassiopeia
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Cassiopeia Build / Runes

the Serpent's Embrace • Platinum+
TOPJUNGLEMIDDLEADCARRYSUPPORT
Best Cassiopeia Build on Mid for patch 14.6. Find the Cassiopeia Runes you are looking for!
1.9%
Pick Rate
51.5%
Win Rate
1.7%
Ban Rate
89,188
Matches

Strong against

Smolder
42.3%
936
Lissandra
42.8%
1,223
Azir
43.8%
1,428
Tristana
44.6%
1,206
Vladimir
45.5%
1,719

Weak against

Xerath
52.8%
1,439
Malzahar
52.7%
2,081
Anivia
52.4%
1,042
Aurelion Sol
52%
3,056
Naafiri
51.5%
1,135

Summoner Spells

FlashTeleport
51.3%
66,767 Matches

Starter Items

Health Potion
2
Tear of the Goddess
51.8%
68,222 Matches

Core Items

Rod of AgesArchangel's StaffRylai's Crystal Scepter
56.3%
23,586 Matches

Late Game Items

Liandry's Torment
Rabadon's Deathcap
Cosmic Drive
55.1%64.5%60.5%

Spell Skill Priority

Twin Fang
E
Noxious Blast
Q
Miasma
W
52%
48,312 Matches
Noxious Blast
Q
2
8
10
12
13
Miasma
W
3
14
15
Twin Fang
E
1
4
5
7
9
Petrifying Gaze
R
6
11

Cassiopeia Runes

PrecisionPrecision
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SorcerySorcery
Nullifying Orb
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
Offense
Offense
Offense
Offense
Flex
Flex
Defense
Flex
Flex

lolvvv Cassiopeia Runes

Cassiopeia Runes
PrecisionPrecision
Press the Attack
0%
Lethal Tempo
0%
Fleet Footwork
0%
Conqueror
100%
Overheal
0%
Triumph
0%
Presence of Mind
100%
Legend: Alacrity
0%
Legend: Tenacity
100%
Legend: Bloodline
0%
Coup de Grace
18%
Cut Down
<1%
Last Stand
81%
SorcerySorcery
Nullifying Orb
0%
Manaflow Band
92%
Nimbus Cloak
0%
Transcendence
71%
Celerity
8%
Absolute Focus
0%
Scorch
28%
Waterwalking
0%
Gathering Storm
<1%
Offense
70%
Offense
0%
Offense
30%
Offense
81%
Flex
0%
Flex
0%
Defense
66%
Flex
0%
Flex
0%

Lore

Ally Tips

Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.

Lead your enemy when targeting with Noxious Blast to ensure the hit.

Enemy Tips

Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.

Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.

Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.