Cassiopeia
B

Cassiopeia Build / Runes

the Serpent's Embrace • Platinum+
TOPJUNGLEMIDDLEADCARRYSUPPORT
Best Cassiopeia Build on Support for patch 16.21. Find the Cassiopeia Runes you are looking for!
0%
Pick Rate
44.2%
Win Rate
1%
Ban Rate
2,471
Matches

Strong against

Swain
44.4%
63
Malphite
45.2%
31
Alistar
50%
50
Senna
50%
70
Maokai
50%
26

Weak against

Xerath
72.7%
44
Zyra
68.9%
45
Pantheon
68.2%
66
Karma
67.3%
55
Vel'Koz
66.7%
33

Summoner Spells

ExhaustFlash
45.2%
608 Matches

Starter Items

Health Potion
2
44.7%
2,104 Matches

Core Items

Celestial OppositionRylai's Crystal ScepterBoots of Swiftness
59.2%
49 Matches

Late Game Items

Archangel's Staff
Liandry's Torment
Zhonya's Hourglass
49.7%54.1%56.1%

Spell Skill Priority

Twin Fang
E
Noxious Blast
Q
Miasma
W
45%
528 Matches
Noxious Blast
Q
2
8
10
12
13
Miasma
W
3
14
15
Twin Fang
E
1
4
5
7
9
Petrifying Gaze
R
6
11

Cassiopeia Runes

SorcerySorcery
Summon Aery
Arcane Comet
Stormraider's Surge
Deathfire Touch
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
PrecisionPrecision
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Adapative Force
Attack Speed
Ability Haste
Adapative Force
Move Speed
Health Scaling
Base Health
Tenacity and Slow Resist
Health Scaling

lolvvv Cassiopeia Runes

Cassiopeia Runes

Lore

Ally Tips

Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.

Lead your enemy when targeting with Noxious Blast to ensure the hit.

Enemy Tips

Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.

Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.

Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.