A
Cassiopeia Build / Runes
the Serpent's Embrace • Platinum+
Best Cassiopeia Build on Top for patch 16.21. Find the Cassiopeia Runes you are looking for!
0.3%
Pick Rate
48.3%
Win Rate
1%
Ban Rate
27,262
Matches
Strong against
43.8%
290
45.2%
509
46.8%
357
48%
392
48%
479
Weak against
57.8%
374
57.4%
310
57.2%
446
56.2%
379
55.9%
585
Summoner Spells
49.9%
4,160 Matches
Starter Items
2
48.7%
18,897 Matches
Core Items
49.4%
3,632 Matches
Late Game Items
53.8%54.2%51.7%
Spell Skill Priority
E
Q
W
52%
5,841 Matches
Q
2
8
10
12
13
W
4
14
15
E
1
3
5
7
9
R
6
11
Cassiopeia Runes
Sorcery
Precision
lolvvv Cassiopeia Runes
Cassiopeia RunesPrecision
0%
0%
0%
100%
0%
0%
100%
0%
100%
0%
0%
3%
97%
Sorcery0%
100%
0%
57%
43%
0%
0%
0%
0%
100%
0%
0%
57%
43%
0%
43%
0%
57%
Lore
Ally Tips
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Enemy Tips
Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.
Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.
Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.