Kai'Sa Build / Runes
Late Game Items
Spell Skill Priority
Mobalytics Kai'Sa RunesMore Kai'Sa Builds
lolvvv Kai'Sa RunesKai'Sa Runes
Try to catch enemy carries alone to burst them with Icathian Rain.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Make sure to buy items that will evolve at least 1 or 2 of your spells.
Kai'Sa Runes is very good at picking off isolated enemies. Stick together against her.
Kai'Sa Runes is very vulnerable to getting outranged by mages and long range carries.
Make sure to place wards in your blind spots so you can see Kai'Sa Runes coming.