B
Cassiopeia Build / Runes
the Serpent's Embrace • Platinum+
Best Cassiopeia Build on Adc for patch 16.21. Find the Cassiopeia Runes you are looking for!
0.2%
Pick Rate
49.5%
Win Rate
1%
Ban Rate
15,116
Matches
Strong against
45%
229
46%
535
46.1%
505
46.9%
228
47.3%
512
Weak against
55.5%
299
55.3%
349
54.6%
174
54.3%
291
53.4%
1,068
Summoner Spells
51%
2,898 Matches
Starter Items
2
49.8%
11,701 Matches
Core Items
52.1%
1,184 Matches
Late Game Items
51.2%52.8%55.3%
Spell Skill Priority
E
Q
W
54%
1,580 Matches
Q
2
8
10
12
13
W
4
14
15
E
1
3
5
7
9
R
6
11
Cassiopeia Runes
Sorcery
Precision
lolvvv Cassiopeia Runes
Cassiopeia RunesSorcery0%
0%
0%
100%
0%
100%
0%
0%
100%
0%
100%
0%
0%
Precision0%
0%
17%
0%
87%
0%
0%
93%
3%
80%
0%
20%
40%
60%
0%
100%
0%
0%
Lore
Ally Tips
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Enemy Tips
Be wary of Cassiopeia Runes's damage potential with Twin Fang when she has you poisoned.
Turn away from Cassiopeia Runes when she is casting Petrifying Gaze to get slowed instead of stunned.
Cassiopeia Runes is a deadly creature bent on manipulating others to her sinister will. Youngest and most beautiful daughter of the noble Du Couteau family of Noxus, she ventured deep into the crypts beneath Shurima in search of ancient power. There, she was bitten by a gruesome tomb guardian, whose venom transformed her into a viper-like predator. Cunning and agile, Cassiopeia Runes now slithers under the veil of night, petrifying her enemies with her baleful gaze.